We successfully performed a total resection of the pulmonary artery tr
unk and replaced it with an equine pericardial xenograft roll in a pat
ient with a recurrent leiomyosarcoma. We believe, based on anatomic an
d embryologic principles, total rather than partial resection of the p
ulmonary artery trunk should be the treatment of choice for primary le
iomyosarcomas of the pulmonary artery.