Background. This study examined the effect of sedation on the rate of
complete colonoscopic examinations by a family physician performing co
lonoscopy at an urban family practice residency. The outcomes of biops
ies and polypectomies performed during the period of the study were al
so evaluated. Methods. Data were prospectively collected on 164 consec
utive colonoscopies. Seventy-three percent (124/164) of the examinatio
ns were training experiences supervised by the first author. The outco
mes of examinations of 126 sedated patients were compared with those o
f 38 nonsedated patients. Patients were not randomly selected. Results
. Examinations of 126 sedated patients were carried out with an 85% re
ach-the-cecum rate compared with a 31% reach-the-cecum rate for 38 non
sedated patients (P < .05). A higher percentage of examinations done w
ithout sedation (16%) were terminated because of pain than were termin
ated in sedated patients (5%) (P < .05). An electrolyte purge solution
was found to be the most effective colonoscopy preparation; only 7% (
7/100) of examinations on patients prepared by this method were termin
ated because of inadequate bowel preparation. Adenomas were found in 1
1% (14/126) of sedated patients and in 8% (3/38) of nonsedated patient
s. Cancer was detected in 4 sedated patients. Conclusion. These findin
gs suggest that sedation in colonoscopy is associated with a higher pe
rcentage of complete examinations. Also, patients prepared with an ele
ctrolyte purge solution tend to have fewer examinations terminated bec
ause of inadequate preparation.