Despite prophylactic therapy, pulmonary embolism remains the leading c
ause of perioperative mortality in patients undergoing total knee arth
roplasty (TKA). We used transoesophageal echocardiography to monitor 2
9 consecutive patients during TKA. Showers of substantial amounts of e
chogenic material, lasting for 3-15 min, were visible in the right atr
ium and ventricle within 10-15 s of tourniquet deflation in all patien
ts. A 3 x 6 mm fresh thrombus was aspirated from the central circulati
on of one patient. Another patient, who had had a Greenfield filter pl
aced for previous thromboembolism, showed very little echogenic materi
al after tourniquet deflation. The composition and importance of these
echogenic emboli remain uncertain.