FINE-NEEDLE ASPIRATION BIOPSY - DERMATOFIBROSARCOMA PROTUBERANS

Dermatofibrosarcoma protuberans (DFSP) represents a spectrum of mesenc hymal spindle cell tumors that typically involve both dermis and subcu tis. Presented herein are six cases of DFSP, four of which were initia lly diagnosed by FNAB. The cytologic features useful in the identifica tion of this lesion on Papanicolaou- and Diff-Quik-stained smears are discussed. Chief among these are the storiform stromal fragments, pres ence of entrapped adipose tissue and the recognition of fibrohistiocyt ic spindle cells. The potential pitfalls and the differential diagnost ic possibilities of spindle-cell lesions, particularly those of fibroh istiocytic origin are discussed.