Late evolutionary stages of the remnants generated by supernovae explo
ding in OB associations are calculated in attempt to explain the origi
n of a 1.5 kpc-diameter hole observed in the HI disk of M101. The asso
ciation is modeled as an extended source of energy. This approach is a
significant improvement of the input physics commonly used to generat
e the hydrodynamic models of remnants. Unfortunately, the models do no
t match the observations: chimneys generated in the HI disk have diame
ters approximately 3 times smaller than the observed hole, and the mas
s escaping from the disk is at least 10 times too small. Two possible
improvements of the theory enabling explanation of the observation are
discussed.