A COMPARISON OF MULTINEPHRON AND SHUNT MODELS OF THE RENAL CONCENTRATING MECHANISM

Authors
WANG H TEWARSON RP JEN JF STEPHENSON JL
Citation
H. Wang et al., A COMPARISON OF MULTINEPHRON AND SHUNT MODELS OF THE RENAL CONCENTRATING MECHANISM, Applied mathematics letters, 6(2), 1993, pp. 61-65
Citations number
17
Journal title
Applied mathematics letters → ACNP
ISSN journal
08939659
Volume
6
Issue
2
Year of publication
1993
Pages
61 - 65
Database
ISI
SICI code
0893-9659(1993)6:2<61:ACOMAS>2.0.ZU;2-D
Abstract
A multinephron model of the inner medullary urinary concentrating mech anism in the mammalian kidney is described. A procedure to represent t he distribution of nephrons with a finite number of different nephron types is introduced. The model is compared with a shunt model. These s tudies show that, for uniform transport permeabilities: (1) 40 properl y weighted nephron types are sufficient to represent the distribution of nephrons; (2) the two models give essentially the same results.