COMPARISON OF GC-MS AND HPLC-UV FOR DETERMINATION OF PROCYMIDONE IN WINE

Temperature-gradient capillary gas chromatography-mass spectrometry wi th selected ion monitoring at m/z 124, 187, and 283 and isocratic reve rsed-phase high-performance liquid chromatography with ultraviolet (UV ) detection at 207 nm were compared for the determination of residual levels of procymidone in wine. Previous extraction was carried out usi ng Sep-Pak C18 cartridges. Calibration plots were linear from 1 to 50 ppm of procymidone. Method detection limits for GC-MS and HPLC-UV were 6 and 10 ppb (w/v), respectively, and percent recoveries were 94.7 +/ - 5.7 % and 96.9 4 +/- 4.3 %. The methods do not give statistically di fferent values, but GC-MS has the advantage of confirming the identity of procymidone, thus increasing the reliability of the residual analy sis.