AN ATOMIC BASIS OF CANCER LANTHANIDE PORPHYRIN PROBES OF ANIMAL TUMORS

Citation
Cc. Wei et al., AN ATOMIC BASIS OF CANCER LANTHANIDE PORPHYRIN PROBES OF ANIMAL TUMORS, Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms, 75(1-4), 1993, pp. 195-199
Citations number
6
Categorie Soggetti
Physics, Nuclear","Nuclear Sciences & Tecnology","Instument & Instrumentation
ISSN journal
0168583X
Volume
75
Issue
1-4
Year of publication
1993
Pages
195 - 199
Database
ISI
SICI code
0168-583X(1993)75:1-4<195:AABOCL>2.0.ZU;2-W
Abstract
We have synthesized a rare earth metal with porphyrin to obtain a lant hanoid porphynato for biomedical applications. Some of the lanthanoid porphynatos are potentially the versatile cancer probes. We report gad olinium hematoporphyrin derivative synthesis and show that PIXE can be used to assess how good the synthesis is and how good the gadolinium hematoporphyrin derivative system can be used as a tumor localizer to probe a malignant neoplasia from its benigh periphery. We show the PIX E spectra of a nude mouse experiment to explain our works. Theoretical ly the present approach can allow us to investigate carcinogenesis at the cell level.