COMPLEMENT ACTIVATION AND SENSITIZING ANTIBODIES IN LYME BORRELIOSIS - A MICROBIAL ADHERENCE IMMOBILIZATION ASSAY FOR BORRELIA-BURGDORFERI (MAIA-BB)

Authors
CACCIAPUOTI B CICERONI L FONTANA L PERRICONE R
Citation
B. Cacciapuoti et al., COMPLEMENT ACTIVATION AND SENSITIZING ANTIBODIES IN LYME BORRELIOSIS - A MICROBIAL ADHERENCE IMMOBILIZATION ASSAY FOR BORRELIA-BURGDORFERI (MAIA-BB), Zentralblatt fur Bakteriologie, 278(1), 1993, pp. 102-111
Citations number
46
Categorie Soggetti
Microbiology,Virology
Journal title
Zentralblatt fur Bakteriologie → ACNP
ISSN journal
09348840
Volume
278
Issue
1
Year of publication
1993
Pages
102 - 111
Database
ISI
SICI code
0934-8840(1993)278:1<102:CAASAI>2.0.ZU;2-S
Abstract
A report is presented about the capability of complement to directly c lump Borrelia burgdorferi. The new phenomenon which has been termed '' microbial adherence'', is either antibody-independent or requires the presence of ''sensitizing'' antibodies depending the strains tested. M icrobial adherence is associated with immobilization and killing of bo rrelias. A microbial adherence immobilization assay for B. burgdorferi (MAIA-BB) was developed to detect sensitizing antibodies in patients with Lyme borreliosis and in B. burgdorferi-infected animals.