Hp. Lefebvre et al., LOCAL INTOLERANCE AFTER INTRAMUSCULAR INJECTION OF A LONG-ACTING FORMULATION IN A COW - CLINICAL BIOCHEMISTRY AND ULTRASONOGRAPHY, Revue de Medecine Veterinaire, 144(3), 1993, pp. 229-233
In a cow, the intramuscular injection of a long-acting formulation of
chloramphenicol determined local muscle damage evidenced by echography
. There was an immediate (from the 10th minute), intense (80 fold peak
increase about the 24th hour) and durable (up to the 11th day) increa
se of plasma creatine kinase activity; the activities of lactate dehyd
rogenase and aminotransferases, as well as potassium concentration wer
e also increased.