Lp. Duan et al., A STUDY OF GASTRIC-EMPTYING IN NONULCER DYSPEPSIA USING A NEW ULTRASONOGRAPHIC METHOD, Scandinavian journal of gastroenterology, 28(4), 1993, pp. 355-360
To ascertain the effect of gastric emptying on the symptoms of non-ulc
er dyspepsia (NUD) patients, we randomly selected 60 NUD patients and,
as control, 26 dyspepsia-free volunteers. We measured the gastric emp
tying time of mixed food (270 kcal), using real-time ultrasonography i
n two ways. NUD patients were divided randomly into two groups and giv
en domperidone or placebo in a double-blind trial. Of the NUD patients
48% had delayed gastric emptying times and associated epigastric pain
, bloating, early satiety, and regurgitation. A prokinetic agent not o
nly improved emptying time but also relieved some of the symptoms of t
he NUD patients. Real-time ultrasonography proved a useful method for
evaluating gastric emptying.