PURPURONE, AN INHIBITOR OF ATP CITRATE LYASE - A NOVEL ALKALOID FROM THE MARINE SPONGE IOTROCHOTA SP

Authors
CHAN GW FRANCIS T THUREEN DR OFFEN PH PIERCE NJ WESTLEY JW JOHNSON RK FAULKNER DJ
Citation
Gw. Chan et al., PURPURONE, AN INHIBITOR OF ATP CITRATE LYASE - A NOVEL ALKALOID FROM THE MARINE SPONGE IOTROCHOTA SP, Journal of organic chemistry, 58(9), 1993, pp. 2544-2546
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
58
Issue
9
Year of publication
1993
Pages
2544 - 2546
Database
ISI
SICI code
0022-3263(1993)58:9<2544:PAIOAC>2.0.ZU;2-B
Abstract
A novel compound, purpurone (1), with ATP-citrate lyase inhibitory act ivity, was isolated from the marine sponge Iotrochota sp. Its structur e was established mainly on the basis of NMR spectroscopic data. Purpu rone represents the first example of a new class of marine products.