EXTRACTIVE METHYLATION OF CLOPAMIDE AND INDAPAMIDE - STRUCTURES OF THE DERIVATIVES

Authors
EHRHARDT JD
Citation
Jd. Ehrhardt, EXTRACTIVE METHYLATION OF CLOPAMIDE AND INDAPAMIDE - STRUCTURES OF THE DERIVATIVES, Biological mass spectrometry, 22(5), 1993, pp. 295-301
Citations number
15
Categorie Soggetti
Spectroscopy,Biophysics
Journal title
Biological mass spectrometry → ACNP
ISSN journal
10529306
Volume
22
Issue
5
Year of publication
1993
Pages
295 - 301
Database
ISI
SICI code
1052-9306(1993)22:5<295:EMOCAI>2.0.ZU;2-G
Abstract
Extractive methylation of clopamide and indapamide gives rise to the f ormation of several derivatives. Their positive and negative ion mass spectra are described and their respective structures established. Thi s derivatization procedure seems to be unsuitable for a quantitative a nalysis of these two diuretics, unless a deuterated analogue or a comp ound with the same chemical functions is used as the internal standard .