B. Slesak et al., INVITRO EFFECTS OF CHELIDONIUM-MAJUS L ALKALOID THIOPHOSPHORIC ACID CONJUGATES (UKRAIN) ON THE PHENOTYPE OF NORMAL HUMAN-LYMPHOCYTES, Drugs under experimental and clinical research, 18, 1992, pp. 17-21
Several plant-derived drugs are used in medical oncology (1-3). The th
iophosphoric acid-alkaloid derivative from the plant Chelidonium majus
L. (Ukrain) has been produced since 1978 by Nowicky. (Austrian Patent
No. 354644, Vienna, 25 January 1980). It has been reported that this
drug may exert therapeutic effects in cancer patients by modulating th
eir immune systems (4, 5-8). The aim of this study was to evaluate in
vitro the possibility that Ukrain may influence the phenotype of lymph
ocyte subpopulations isolated from healthy donors.