EFFECT OF 3 MONTHS TREATMENT WITH UKRAIN ON PERIPHERAL-BLOOD MORPHOLOGY IN RODENTS

Studies on Albino Swiss mice and Wistar rats have demonstrated that Uk rain administered intraperitoneally (ip.) for three months produces th e following effects in the haematologic parameters: increased leucocyt es and decreased thrombocytes. The haemoglobin and erythrocyte levels, as well as haematocrit value, were unchanged. In the leucogram change s were observed; i.e., a fall in the number of neutrophil segments and an increase in the lymphocyte count. The erythrocyte indices, P.C.V., M.C.V., M.C.H, and M.C.H.C. were not changed by a period of three mon ths i.p. Ukrain administration. The observed changes were more marked in female than in male animals and were greater in mice than in rats.