INVIVO ACQUIRED-RESISTANCE - LESSONS LEARNED FROM A PERITONITIS MODEL

Authors
Citation
B. Marchou, INVIVO ACQUIRED-RESISTANCE - LESSONS LEARNED FROM A PERITONITIS MODEL, Medecine et maladies infectieuses, 23(3), 1993, pp. 221-223
Citations number
NO
Categorie Soggetti
Infectious Diseases
ISSN journal
0399077X
Volume
23
Issue
3
Year of publication
1993
Pages
221 - 223
Database
ISI
SICI code
0399-077X(1993)23:3<221:IA-LLF>2.0.ZU;2-C
Abstract
During recent years development of resistance in bacterial species as Enterobacter cloacae or Pseudomonas aeruginosa after therapy with newe r beta-lactams or fluoroquinolones has been well documented. A murine model of peritonitis has been developed to study this emergence of res istance due to the selection of resistant variants under various antib iotic regimens and to confirm the prophylactic role of antibiotic comb inations to prevent therapeutic failure,