A CA-2-INDEPENDENT PROTEIN-KINASE-C, NPKC-ETA - ITS STRUCTURE, DISTRIBUTION AND POSSIBLE FUNCTION()

Authors
HASHIMOTO Y OSADA S OHNO S KUROKI T
Citation
Y. Hashimoto et al., A CA-2-INDEPENDENT PROTEIN-KINASE-C, NPKC-ETA - ITS STRUCTURE, DISTRIBUTION AND POSSIBLE FUNCTION(), Tohoku Journal of Experimental Medicine, 168(2), 1992, pp. 275-278
Citations number
3
Categorie Soggetti
Medicine, Research & Experimental
Journal title
Tohoku Journal of Experimental Medicine → ACNP
ISSN journal
00408727
Volume
168
Issue
2
Year of publication
1992
Pages
275 - 278
Database
ISI
SICI code
0040-8727(1992)168:2<275:ACPN-I>2.0.ZU;2-8
Abstract
Protein kinase C consists of a protein family which can be classified into two major groups: Ca2+-dependent conventional protein kinase C an d Ca2+-independent novel protein kinase C (nPKC). Among eight known me mbers of protein kinase C family, we found that nPKCeta (eta) isolated from cDNA library of mouse skin, is most abundant in epithelial tissu es including skin and epithelia of digestive and respiratory tracts. T hese data suggest potential role of this isoform in growth, differenti ation and carcinogenesis of epithelial tissues.