ADRENOLEUCOMYELONEUROPATHY IN AN ADULT

We report a case of adrenomyeloneuropathy in a 35-year-old man. He exp erienced acute adrenal insufficiency at 29 years of age, followed by p sychic disorders and mental deterioration, then spastic paraparesia, d ysarthria and peripheral neuropathy. MRI showed high-intensity signal areas in the cerebellum and periventricular white matter. Clinical sym ptoms, neurophysiological and neuroradiological examinations disclosed both features of adrenoleucodystrophy and adrenomyeloneuropathy. This indicates that adrenoleucodystrophy and adrenomyeloneuropathy probabl y represent two portions of the same entity.