Cosmological topological defects as well as some nonstandard inflation
models can give rise to non-Gaussian density perturbations. Skewness
and kurtosis are the third and fourth moments that measure the deviati
on of a distribution from a Gaussian. Measurement of these moments for
the cosmological density field and for the microwave background tempe
rature anisotropy can provide a test of the Gaussian nature of the pri
mordial fluctuation spectrum. In the case of the density field, the im
portance of measuring the kurtosis is stressed since it will be preser
ved through the weakly nonlinear gravitational evolution epoch. Curren
t constraints on skewness and kurtosis of primeval perturbations are o
btained from the observed density contrast deltarho/rho on small scale
s and from recent COBE observations of temperature anisotropies on lar
ge scales. It is also shown how, in principle, future microwave anisot
ropy experiments might be able to reveal the initial skewness and kurt
osis. It is shown that present data argue that if the initial spectrum
is adiabatic, then it is probably Gaussian, but non-Gaussian isocurva
ture fluctuations are still allowed, and these are what topological de
fects provide.