A. Chatterjee et al., REDUCTION IN INTRAOCULAR-PRESSURE AFTER EXCIMER-LASER PHOTOREFRACTIVEKERATECTOMY - CORRELATION WITH PRETREATMENT MYOPIA, Ophthalmology, 104(3), 1997, pp. 355-359
Purpose: The authors relate the observed reduction in intraocular pres
sure (IOP) after excimer laser treatment to the degree of myopia treat
ed, Background: Intraocular pressure, measured by both Goldmann applan
ation and noncontact tonometry, has been reported to decrease after ex
cimer laser photorefractive keratectomy (PRK). However, IOP readings a
fter excimer laser PRK might be inaccurate as a consequence of changes
in both the thickness and curvature of the cornea. Methods: Baseline
IOP readings were measured by noncontact tonometry in each eye of a gr
oup of 1320 patients at the time of their initial consultation. These
were compared to readings obtained before treatment of the second eye,
which took place a minimum of 4 months later, The untreated eyes serv
ed as controls. The paired Student's t test was used for statistical a
nalysis, Results: After PRK, a decrease was observed in the IOP of tre
ated eyes that was related to the, degree of myopia treated, A signifi
cant difference was observed between treated and untreated eyes (P < 0
.0000). Conclusions: The IOP measured after PRK for myopia-may be redu
ced because of changes in corneal thickness (absence of Bowman's membr
ane and central thinning) and topography. This is of particular releva
nce when monitoring the IOP of those patients who are given steroid dr
ops to prevent regression, It also may be of importance in the managem
ent of any future glaucoma.