THE INVOLVEMENT OF POLYMORPHONUCLEAR LEUKOCYTES IN THE PATHOGENESIS OF BRONCHOPNEUMONIA IN CALVES .6. SUPEROXIDE-DISMUTASE AND LIPOPROTEIN-LIPASE ACTIVITIES

Authors
LEDWOZYW A STOLARCZYK H
Citation
A. Ledwozyw et H. Stolarczyk, THE INVOLVEMENT OF POLYMORPHONUCLEAR LEUKOCYTES IN THE PATHOGENESIS OF BRONCHOPNEUMONIA IN CALVES .6. SUPEROXIDE-DISMUTASE AND LIPOPROTEIN-LIPASE ACTIVITIES, Acta veterinaria Hungarica, 40(4), 1992, pp. 267-277
Citations number
NO
Categorie Soggetti
Veterinary Sciences
Journal title
Acta veterinaria Hungarica → ACNP
ISSN journal
02366290
Volume
40
Issue
4
Year of publication
1992
Pages
267 - 277
Database
ISI
SICI code
0236-6290(1992)40:4<267:TIOPLI>2.0.ZU;2-I
Abstract
The kinetics of superoxide anion production in polymorphonuclear leuko cytes of bronchopneumonic calves, as well as superoxide dismutase and lipoprotein lipase activities in the blood plasma of these animals wer e studied. Granulocytes of bronchopneumonic calves were found to produ ce 10 times as much O2- radicals as those of healthy animals. Superoxi de dismutase and lipoprotein lipase activities were lower in the plasm a of bronchopneumonic calves. Escherichia coli endotoxin was found to stimulate superoxide anion production in polymorphonuclear leukocytes in a dose-dependent t manner. These facts suggest that an endogenous m ediator, probably cachectin or some other monokine(s), plays a role in granulocyte activation during calf bronchopneumonia.