ACTIVITY OF SERUM CREATINE-KINASE, LACTATE-DEHYDROGENASE AND LD ISOENZYMES IN PIGLETS AFFECTED WITH CONGENITAL TREMOR - A CASE-REPORT

The activities of serum creatine kinase (CK), lactat dehydrogenase (LD ) and LD isoenzymes were studied in 14 Prestice black pied pigs from a herd affected with congenital tremor. Mean CK activity was 19.57 +/- 3.56 mukat . l-1 for 6 adult pigs, and it was 21.03 +/- 1.33 mukat . l -1 and 20.42 +/- 1.23 mukat . l-1 for the affected (n = 5) and control (n = 3) piglets, respectively. No significant differences were demons trable between the groups in CK activity. Total serum LD and LD-4 as w ell as LD-5 isoenzyme activities were higher in sows. Piglets affected with congenital tremor showed an increase in total LD enzyme and LD-5 isoenzyme activity. It is concluded that no relationship exists betwe en congenital tremor and serum CK activity in piglets. At the same tim e, there is a positive relationship between congenital tremor and sign ificantly (P < 0.01) elevated LD enzyme and LD-5 isoenzyme activity. T he results allow us to suggest that total lactate dehydrogenase and LD -5 isoenzyme activities could be used as biological markers of congeni tal tremor in piglets.