IS THERE LIPID-PEROXIDATION INDUCED MALONDIALDEHYDE PRODUCTION DURINGEGG-SHELL FORMATION

Authors
Citation
M. Mezes et A. Hidas, IS THERE LIPID-PEROXIDATION INDUCED MALONDIALDEHYDE PRODUCTION DURINGEGG-SHELL FORMATION, Acta veterinaria Hungarica, 40(4), 1992, pp. 297-301
Citations number
NO
Categorie Soggetti
Veterinary Sciences
Journal title
ISSN journal
02366290
Volume
40
Issue
4
Year of publication
1992
Pages
297 - 301
Database
ISI
SICI code
0236-6290(1992)40:4<297:ITLIMP>2.0.ZU;2-Q
Abstract
The marked increase observed in malondialdehyde concentration of the b lood plasma and liver of laying hens during egg shell formation in a p revious experiment (Mezes and Lencses, 1985) were explained as a possi ble consequence of physiologically controlled lipid peroxidation. In t his experiment, 54-week-old laying hens were treated intrauterinally w ith indomethacin (1.0 and 2.0 mg/kg body mass) after oviposition. Two other groups of hens were treated per os with excess amounts of vitami n E (100 and 200 mg/bird). The higher dose of indomethacin significant ly decreased the PGF2alpha production and malondialdehyde content of t he sell gland, as well as the malondialdehyde concentration of the pla sma. The excess amount of vitamin E had the same effect. The results s uggest that during egg shell formation malondialdehyde is derived from prostanoid biosynthesis rather than from a free-radical initiated lip id peroxidative process. On the other hand, the excess amount of vitam in E inhibited prostaglandin biosynthesis as well as malondialdehyde p roduction.