M. Mezes et A. Hidas, IS THERE LIPID-PEROXIDATION INDUCED MALONDIALDEHYDE PRODUCTION DURINGEGG-SHELL FORMATION, Acta veterinaria Hungarica, 40(4), 1992, pp. 297-301
The marked increase observed in malondialdehyde concentration of the b
lood plasma and liver of laying hens during egg shell formation in a p
revious experiment (Mezes and Lencses, 1985) were explained as a possi
ble consequence of physiologically controlled lipid peroxidation. In t
his experiment, 54-week-old laying hens were treated intrauterinally w
ith indomethacin (1.0 and 2.0 mg/kg body mass) after oviposition. Two
other groups of hens were treated per os with excess amounts of vitami
n E (100 and 200 mg/bird). The higher dose of indomethacin significant
ly decreased the PGF2alpha production and malondialdehyde content of t
he sell gland, as well as the malondialdehyde concentration of the pla
sma. The excess amount of vitamin E had the same effect. The results s
uggest that during egg shell formation malondialdehyde is derived from
prostanoid biosynthesis rather than from a free-radical initiated lip
id peroxidative process. On the other hand, the excess amount of vitam
in E inhibited prostaglandin biosynthesis as well as malondialdehyde p
roduction.