CLINICAL-EVALUATION OF THE FUNCTIONAL-ACTIVITY OF MACROPHAGES IN PATIENTS WITH PROTRACTED DYSENTERY AND ITS CORRECTION WITH LYSOZYME AND VITAMIN-E

Authors
YUSHCHUK ND ZYUZIN VA FROLOV VM PERESADIN NA
Citation
Nd. Yushchuk et al., CLINICAL-EVALUATION OF THE FUNCTIONAL-ACTIVITY OF MACROPHAGES IN PATIENTS WITH PROTRACTED DYSENTERY AND ITS CORRECTION WITH LYSOZYME AND VITAMIN-E, Zurnal mikrobiologii, epidemiologii i immunobiologii, (11-12), 1992, pp. 57-59
Citations number
6
Categorie Soggetti
Microbiology,Immunology,"Public, Environmental & Occupation Heath
Journal title
Zurnal mikrobiologii, epidemiologii i immunobiologii → ACNP
ISSN journal
03729311
Issue
11-12
Year of publication
1992
Pages
57 - 59
Database
ISI
SICI code
0372-9311(1992):11-12<57:COTFOM>2.0.ZU;2-T
Abstract
Prospects for the correction of disturbances in the macrophagal system with a combination of lysozyme and vitamin E in patients with a protr acted course of dysentery caused by Shigella flexneri 1b were studied. The phagocytic activity of macrophages (PAM) was found to be suppress ed as early as at the beginning of the disease. Out of 38 persons repe atedly found to release shigellae 24 were administered polychemotherap y. PAM indices in patients treated with lysozyme and tocopherol acetat e were likely to normalize, this being indicative of the positive effe ct of these preparations on the functional activity of the macrophagal system.