Thoracoscopy was performed in 76 patients with chronic pleural effusio
ns in which thoracocentesis and blind needle biopsy failed to reach a
precise diagnosis. Analysis of thoracoscopic biopsies provided a defin
itive diagnosis in 53 of the 76 subjects. The diagnoses included 35 ma
lignant diseases in which the macroscopic appearance was diagnostic in
only 27 patients. Among these 76 patients, a talc poudrage was perfor
med in the management of recurrent effusion in 33 patients. No recurre
nce of pleural effusion was observed after 1 month in 87% and after 6
months in 76% of patients with recurrent pleural effusion. We confirm
that thoracoscopy is a safe and useful technique for the diagnosis of
pleural effusion which substantially decreases the necessity for diagn
ostic thoracotomy and that talc poudrage is effective to achieve pleur
odesis.