RECURRENT MENINGOCOCCAL INFECTIONS IN A PATIENT WITH CONGENITAL C5 DEFICIENCY

Authors
BOLS A JANSSENS J PEETERMANS W STEVENS E BOBBAERS H
Citation
A. Bols et al., RECURRENT MENINGOCOCCAL INFECTIONS IN A PATIENT WITH CONGENITAL C5 DEFICIENCY, Acta Clinica Belgica, 48(1), 1993, pp. 42-47
Citations number
NO
Categorie Soggetti
Medicine, General & Internal
Journal title
Acta Clinica Belgica → ACNP
ISSN journal
00015512
Volume
48
Issue
1
Year of publication
1993
Pages
42 - 47
Database
ISI
SICI code
0001-5512(1993)48:1<42:RMIIAP>2.0.ZU;2-V
Abstract
A congenital C5 deficiency was the cause of recurrent meningococcal di sease in a 27-year-old man. The lack of serum bactericidal activity ac counts for the higher incidence and the different course of Neisseria infections in patients with a deficiency of the late complement compon ents. Early antibiotic treatment and vaccination with a capsular polys accharide meningococcal vaccine (A,C,Y,W-135) should be considered.