The purpose of the present study was to compare the performance in sev
eral neuropsychological tasks, as cognitive markers of vulnerability t
o schizophrenia, of two normal population samples classified as high a
nd low psychometrically schizotypal, according to MSTQ (Rawlings y Mac
Farlane, 1994) and O-LIFE (Mason, Claridge and Jackson, 1994), as an e
xternal validation procedure. Thirty three secondary school and 11 col
lege students were selected from a normal sample of 185 subjects. The
YSR (Achenback and Edelbrock, 1987) was also completed by the adolesce
nts sample. Results fail to confirm differences between high and low p
sychometrically identified schizotypic individuals, casting some doubt
s about the usefulness of the questionnaries as early detection proced
ures of risk for schizophrenic spectrum disorders. Possible causes of
the negative results are analysed and some suggestions are offered for
future research.