A subtractive time-of-flight technique for magnetic resonance angiogra
phy is described. In this approach, the arterial supply to an organ is
inverted in a steady-state fashion by applying off-resonance irradiat
ion in the presence of a linear magnetic field gradient. An angiogram
is formed by subtracting an image acquired with arterial inversion fro
m a control image acquired with no arterial inversion. A single coll i
s used to apply both the inversion and observation pulses. Intracrania
l angiograms obtained from normal volunteers using a two-dimensional p
rojective implementation of this technique at 1.5 T illustrate excelle
nt small vessel detail and background suppression.