A 29-year-old female intravenous drug abuser infected with the human i
mmunodeficiency virus suffered recurrent, bilateral corneal infections
over an 11-month period. Multiple infectious organisms were responsib
le, including capnocytophaga species, Candida albicans, Staphylococcus
aureus, coagulase-negative staphylococcus, and a-streptococcus. One e
ye was eviscerated because of corneal perforation and loss of vision;
the second eye has maintained good vision. Predisposing factors usuall
y associated with corneal infections were absent. Treatment was compli
cated by extremely poor patient compliance, ongoing intravenous drug a
buse, and concurrent multiple extraocular medical problems.