Zq. You et M. Koreeda, AXIAL SELECTIVITY OF 1,2-NUCLEOPHILIC ADDITIONS TO 2-(ALKYLIDENE)CYCLOHEXANONES - IS IT HIGHER THAN THAT OF 2-CYCLOHEXENONES, Tetrahedron letters, 34(17), 1993, pp. 2745-2748
2-(Alkylidene)cyclohexanones embedded in steroid systems underwent 1.2
-addition of both small and sterically demanding nucleophiles to yield
exclusively the axial adducts, supporting the suggestion that 2-(alky
lidene)cyclohexanones appear to have intrinsically higher axial select
ivity than 2-cyclohexenones.