HIGHLY REGIOSELECTIVE IRON-PROMOTED HYDROCARBOXYLATION OF STYRENE

Authors
BRUNET JJ NEIBECKER D SRIVASTAVA RS
Citation
Jj. Brunet et al., HIGHLY REGIOSELECTIVE IRON-PROMOTED HYDROCARBOXYLATION OF STYRENE, Tetrahedron letters, 34(17), 1993, pp. 2759-2762
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
17
Year of publication
1993
Pages
2759 - 2762
Database
ISI
SICI code
0040-4039(1993)34:17<2759:HRIHOS>2.0.ZU;2-6
Abstract
The reaction of Li[HFe(CO)4] with styrene under carbon monoxide (1 atm ) in a H2O / iPrOH / LiOH system promotes a highly regioselective (98% ) hydrocarboxylation to 2-phenylpropionic acid. In contrast, when cond ucted under argon, the reaction predominantly (90%) leads to 3-phenylp ropionic acid.