PREGNANCY COMPLICATED BY GORHAM DISEASE

Background: A pregnancy with Gorham disease (massive osteolysis syndro me) is described. To our knowledge, this is the first reported case of a pregnancy associated with this disease. Case: A 25-year-old woman w as seen for pre-conception counseling with the diagnosis of Gorham dis ease. Before pregnancy, magnetic resonance imaging confirmed a stable disease process. The woman and fetus were followed during pregnancy wi th ultrasound and consultations. Severe pre-eclampsia developed at del ivery, with a significant thrombocytopenia. We delivered the infant by low forceps, with a good outcome. Subsequently, the mother and child were doing well at 18 months postpartum. Conclusion: We briefly review this rare bone disease as it relates to pregnancy and provide informa tion for pre-conception counseling.