METASTATIC PLACENTAL LYMPHOMA ASSOCIATED WITH MATERNAL HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION

Background: Pregnancy complicated by maternal human immunodeficiency v irus (HIV) infection is increasing in frequency. This report describes a maternal malignancy associated with HIV infection that may complica te pregnancy. Case: A 33-year-old primigravida was delivered by cesare an. Histologic examination of the placenta revealed the presence of me tastatic non-Hodgkin lymphoma of B-cell origin. The patient was then f ound to be infected with HIV. Nine months postpartum, she was diagnose d with immunoblastic lymphoma. She is currently undergoing chemotherap y. Conclusion: Non-Hodgkin lymphoma of B-cell origin is an indication of AIDS. Pregnancies associated with maternal HIV infection may be com plicated by this malignancy, which may metastasize to the products of conception. Careful examination of the placenta can detect metastases in women with non-Hodgkin B-cell lymphoma.