Aj. Peters et al., SALPINGITIS OR OOPHORITIS - WHAT CAUSES FEVER FOLLOWING OOCYTE ASPIRATION AND EMBRYO TRANSFER, Obstetrics and gynecology, 81(5), 1993, pp. 876-877
Background: Febrile morbidity following in vitro fertilization and emb
ryo transfer (IVF-ET) is a rare but possibly serious complication. Thi
s report describes a case of salpingitis after IVF-ET and discusses th
e possible reasons for febrile morbidity following this common procedu
re. Case: A 37-year-old woman undergoing IVF-ET for tubal factor infer
tility developed sudden, severe pelvic pain, fever, and leukocytosis 2
4 hours after ET. Laparoscopy revealed bilateral suppurative pyosalpin
ges with cystic, hemorrhagic ovaries. Pain, fever, and leukocytosis re
solved with conservative surgery and intravenous antibiotic therapy. C
onclusions: This case presents laparoscopic documentation of a rare co
mplication of oocyte aspiration and/or ET, namely, salpingitis. Possib
ilities for the development of salpingitis following IVF-ET include ac
tivation of quiescent bacteria within the fallopian tubes from a previ
ous pelvic infection, puncture of the bowel during oocyte aspiration,
inoculation of the pelvis with cervicovaginal flora during oocyte aspi
ration, and introduction of bacteria-laden secretions or air into the
fallopian tubes during ET. Although rare, the possibility of severe pe
lvic infection following IVF-ET warrants consideration of prophylactic
antibiotic coverage.