DEVELOPMENT OF VAGINAL ADENOSIS FOLLOWING COMBINED 5-FLUOROURACIL ANDCARBON-DIOXIDE LASER TREATMENTS FOR DIFFUSE VAGINAL CONDYLOMATOSIS

Background: The management of vaginal human papilloma-virus (HPV) lesi ons may be difficult. We report an unusual long-term consequence of tr eatment. Case: A 40-year-old woman presented with vaginal adenosis fol lowing treatment of multiple vaginal condylomata by endovaginal applic ations of 5% 5-fluorouracil cream and vaporization of the remaining su bclinical condylomata by CO2 laser. Conclusion: The approach to the ma nagement of vaginal condylomatosis should take into consideration the possible later occurrence of adenosis.