Pw. Lu et Ct. Cowell, COMBINED THERAPY WITH GROWTH-HORMONE AND OXANDROLONE IN ADOLESCENT GIRLS WITH TURNER SYNDROME, Journal of paediatrics and child health, 29(1), 1993, pp. 40-42
Five adolescent girls with Turner syndrome (mean age 13.9 years, mean
bone age 12.0 years) were treated with both recombinant human growth h
ormone (rhGH) and oxandrolone for 2 years with an average increment in
height of 13.4 cm. The mean bone age advanced by only 1.2 years, prov
iding an increase in the mean estimated mature height of 9.2 cm. We co
nclude that rhGH and oxandrolone benefit older teenagers with Turner s
yndrome because of an increased growth rate with slow progression of s
keletal maturation.