FIBRODYSPLASIA OSSIFICANS PROGRESSIVA AND SYNOVIAL CHONDROMATOSIS

Authors
KALIFA G ADAMSBAUM C JOBDESLANDE C DUBOUSSET J
Citation
G. Kalifa et al., FIBRODYSPLASIA OSSIFICANS PROGRESSIVA AND SYNOVIAL CHONDROMATOSIS, Pediatric radiology, 23(2), 1993, pp. 91-93
Citations number
9
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging",Pediatrics
Journal title
Pediatric radiology → ACNP
ISSN journal
03010449
Volume
23
Issue
2
Year of publication
1993
Pages
91 - 93
Database
ISI
SICI code
0301-0449(1993)23:2<91:FOPASC>2.0.ZU;2-J
Abstract
Two cases of an unusual association - fibrodysplasia ossificans progre ssiva and synovial chondromatosis - in non-related children are presen ted. This association does not seem coincidental and raises several qu estions about the pathogenesis. A genetic hypothesis related to G prot eins is proposed. This is supported by the fact that such abnormalitie s have been demonstrated in pseudohypoparathyroidism and fibrous dyspl asia; these diseases can also be associated with fibrodysplasia ossifi cans progressiva.