Vascular malformations (VMs), including haemangioma, of the upper gast
rointestinal tract, are rare causes of bleeding. Bleeding from these l
esions is often recurrent and diagnosis is often delayed for months to
years. A patient with severe, recurrent upper gastrointestinal bleedi
ng requiring repeated hospitalization and blood transfusions is presen
ted. Upper endoscopy, barium meal and small bowel enteroclysis were ne
gative. Selective mesenteric angiography revealed a VM in the second p
art of the duodenum. Segmental resection of the duodenum was performed
and microscopical examination showed cavernous haemangioma. VM should
be considered in patients with recurrent gastrointestinal bleeding an
d negative conventional investigations. Mesenteric angiography may be
the only investigation which will identify these lesions. Results afte
r excision are excellent.