AMINOGLUTETHIMIDE (AG) AND HYDROCORTISONE (HC) IN BONE METASTASES - ARETROSPECTIVE STUDY

Authors
BONNETERRE J ADENIS A PION JM CAMBIER L KAMUS E HECQUET B
Citation
J. Bonneterre et al., AMINOGLUTETHIMIDE (AG) AND HYDROCORTISONE (HC) IN BONE METASTASES - ARETROSPECTIVE STUDY, Journal of steroid biochemistry and molecular biology, 44(4-6), 1993, pp. 693-696
Citations number
6
Categorie Soggetti
Biology,"Endocrynology & Metabolism
Journal title
Journal of steroid biochemistry and molecular biology → ACNP
ISSN journal
09600760
Volume
44
Issue
4-6
Year of publication
1993
Pages
693 - 696
Database
ISI
SICI code
0960-0760(1993)44:4-6<693:A(AH(I>2.0.ZU;2-3
Abstract
The response rate in bone metastases in 57 patients treated with amino glutethimide and hydrocortisone was retrospectively assessed. All the X-rays were reviewed by two senior radiologists. A response was observ ed in 23% of the patients, a stabilization in 32%. The survival was no t different whether a response or stabilization was observed. Converse ly, survival was significantly worse in patients who experienced a pro gressive disease.