RECURRENCE OF PRIMARY BILIARY-CIRRHOSIS AFTER LIVER-TRANSPLANTATION FOLLOWING FK506-BASED IMMUNOSUPPRESSION

Authors
WONG PYN PORTMANN B OGRADY JG DEVLIN JJ HEGARTY JE TAN KC WILLIAMS R
Citation
Pyn. Wong et al., RECURRENCE OF PRIMARY BILIARY-CIRRHOSIS AFTER LIVER-TRANSPLANTATION FOLLOWING FK506-BASED IMMUNOSUPPRESSION, Journal of hepatology, 17(3), 1993, pp. 284-287
Citations number
10
Categorie Soggetti
Gastroenterology & Hepatology
Journal title
Journal of hepatology → ACNP
ISSN journal
01688278
Volume
17
Issue
3
Year of publication
1993
Pages
284 - 287
Database
ISI
SICI code
0168-8278(1993)17:3<284:ROPBAL>2.0.ZU;2-S
Abstract
We report two cases of recurrence of primary biliary cirrhosis (PBC) i n the transplanted liver whilst maintained on a FK506-based immunosupp ressive regime, the first to be described. One patient experienced sym ptoms in association with the development of cholestasis. In both ther e was a persistence of serological markers of PBC and liver histology revealed florid bile duct destruction and a granulomatous reaction.