EFFECTS OF ETHANOL AND DIAZEPAN ON AG-NOR NEURONAL-ACTIVITY IN THE MEDIAL MAMMILLARY NUCLEUS

It is intended here to study the disorders produced on mammillary bodi es at both behavioural and morphological levels after diazepam and alc ohol administration. For this purpose, 3 groups of rats were used, tes ting them in the water T-maze trial. One of the groups was treated wit h diazepam, another group alcoholized and the third was control group. The reaction time was recorded and also the errors commited in the la st day. Histological analysis was made by evaluation of the number of Ag-NORs and the surface of these in each neuronal nucleus. The results show a statistically significant decrease in reaction time throughout the learning period, with almost no errors. There are not any differe nces in the estimated NOR surface of the experimental groups. However, differences were reported concerning the number of NOR quantified amo ng the different treated groups in relation to control group.