CONFORMATIONAL RECOGNITION OF RA-XII BY 80S RIBOSOMES - A DIFFERENTIAL LINE BROADENING STUDY IN H-1-NMR SPECTROSCOPY

Authors
MORITA H YAMAMIYA T TAKEYA K ITOKAWA H SAKUMA C YAMADA J SUGA T
Citation
H. Morita et al., CONFORMATIONAL RECOGNITION OF RA-XII BY 80S RIBOSOMES - A DIFFERENTIAL LINE BROADENING STUDY IN H-1-NMR SPECTROSCOPY, Chemical and Pharmaceutical Bulletin, 41(4), 1993, pp. 781-783
Citations number
12
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Chemical and Pharmaceutical Bulletin → ACNP
ISSN journal
00092363
Volume
41
Issue
4
Year of publication
1993
Pages
781 - 783
Database
ISI
SICI code
0009-2363(1993)41:4<781:CRORB8>2.0.ZU;2-D
Abstract
H-1 NMR spectroscopy has been used to demonstrate specific binding of rat 80S ribosomes to the major conformer of an antitumor bicyclic hexa peptidic glucoside, RA-XII, isolated from Rubia cordifolia, in a fast exchange process.