THE GENOME OF EQUINE HERPESVIRUS TYPE-2 HARBORS AN INTERLEUKIN-10 (IL10)-LIKE GENE

Authors
RODE HJ JANSSEN W ROSENWOLFF A BUGERT JJ THEIN P BECKER Y DARAI G
Citation
Hj. Rode et al., THE GENOME OF EQUINE HERPESVIRUS TYPE-2 HARBORS AN INTERLEUKIN-10 (IL10)-LIKE GENE, Virus genes, 7(1), 1993, pp. 111-116
Citations number
22
Categorie Soggetti
Genetics & Heredity",Virology
Journal title
Virus genes → ACNP
ISSN journal
09208569
Volume
7
Issue
1
Year of publication
1993
Pages
111 - 116
Database
ISI
SICI code
0920-8569(1993)7:1<111:TGOEHT>2.0.ZU;2-R
Abstract
A gene was identified within the DNA sequences of the EcoRI DNA fragme nt N (4.3 kbp) of the genome of equine herpesvirus type 2 (EHV-2) codi ng for a protein (179 amino acid residues) homologous to the cytokine synthesis inhibitory factor (CSIF; interleukin 10) of the human and mo use, and to the Epstein-Barr virus (EBV) protein BCRF1. This finding i s further significant evidence that the interleukin 10 (IL-10) and/or IL-10-like gene can indeed be present in the genomes of members of the herpesviral family.