Jh. Aiken et Cw. Huie, USE OF A MICROEMULSION SYSTEM TO INCORPORATE A LIPOPHILIC CHIRAL SELECTOR IN ELECTROKINETIC CAPILLARY CHROMATOGRAPHY, Chromatographia, 35(7-8), 1993, pp. 448-450
The separation of (1R, 2S) and (1S, 2R)-ephedrine using microemulsion
electrokinetic capillary chromatography is reported. The lipophilic ch
iral selector, (2R, 3R)-di-n-butyl tartrate (0.5 % w/w), was introduce
d into the electrophoretic buffer consisting of 0.6 % (w/w) sodium dod
ecyl sulfate (SDS) and 1.2 % (w/w) 1-butanol in 15 mM tris-hydroxyamin
omethane buffer (pH 8.1). The two isomers of ephedrine were separated
with excellent resolution.