SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL-ACTIVITY OF COBALT(II), NICKEL(II), COPPER(II) AND ZINC(II) CHLORIDE COMPLEXES WITH VALERALDEHYDE BENZOYLHYDRAZONE AND VALERALDEHYDE ISONICOTINOYLHY DRAZONE

Complexes of the title ligands (Schiff bases) viz. valeraldehyde benzo ylhydrazone, CH3(CH2)3 CH=NN HCOC6H5' (VB H ) , and valeraldehyde ison icotinoylhydrazone, CH3(CH2)3CH=NNHCOC5H4N, (VINH), of the general com position [ML2Cl2].xH2O (where M = Co(II) , Ni(II) , Cu(II) and Zn(II) ; L = VBH and VINH and x = 0.3) were prepared and characterized by ele mental analyses, infrared, electronic and ESR spectra, magnetic moment s, molar conductance and X-ray diffraction data. The complexes are spi n free pseudo-octahedral and the ligands bond to the metal ion via >C= O and >C=N - groups. The ESR spectra of the Cu(II) complexes indicate a dimeric, tetragonally distorted octahedral stereochemistry. Lattice constants of the Cu(II) and Co(II) complexes indicate an orthorhombic microcrystalline structure. The complexes show moderate activity again st fungi and bacteria.