CLINICAL USE OF RECOMBINANT GONADOTROPINS (FSH, LH, HCG)

Authors
ANTOINE JM LOUMAYE E ALVAREZ S MERVIEL P CORNET D MANDELBAUM J SALATBAROUX J
Citation
Jm. Antoine et al., CLINICAL USE OF RECOMBINANT GONADOTROPINS (FSH, LH, HCG), Contraception fertilite sexualite, 25(2), 1997, pp. 141-146
Citations number
45
Categorie Soggetti
Obsetric & Gynecology
Journal title
Contraception fertilite sexualite → ACNP
ISSN journal
11651083
Volume
25
Issue
2
Year of publication
1997
Pages
141 - 146
Database
ISI
SICI code
1165-1083(1997)25:2<141:CUORG(>2.0.ZU;2-1
Abstract
The production of recombinant gonadotropins is independent of urine co llection. They have a high specific activity and a better batch to bat ch consistency than urinary gonadotropins. In our IVF programme 62 nor mo-ovulatory patients less than 38 years old, with tubal or idiopathic infertility and normal sperm, were treated by r-FSH and randomized in to four groups : with or without LHRH agonist, step-up or step-down st imulation. The overall results were higher in the agonist groups, but did not reveal any significant difference between step-up and step-dow n stimulation.