F. Herbst et al., FUNCTIONAL DETERMINANTS AFTER RESTORATIVE PROCTOCOLECTOMY AND ILEAL POUCH-ANAL ANASTOMOSIS, Wiener Klinische Wochenschrift, 105(9), 1993, pp. 250-254
A prospective study was undertaken in 17 patients undergoing restorati
ve proctocolectomy for ulcerative colitis (13 patients) or familial ad
enomatous polyposis (4 patients) to determine relationship between pre
- and postoperative anal sphincter function, pouch characteristics and
functional results. Postoperatively all manometric parameters were si
gnificantly reduced and remained so permanently. Only squeeze pressure
rose to normal values again. The most important factor for a favourab
le functional outcome was pouch volume. A capacious reservoir was asso
ciated with a low stool frequency, low risk of incontinence and genera
l success of the operation, as assessed subjectively. Perianal sorenes
s with considerable skin problems occurred frequently when resting and
squeeze pressures were markedly reduced postoperatively.