The eye movements of a reader during interpretation of digital chest r
adiographs can provide valuable information for lesion detection. Meas
ures of eye movements leg, the locations and durations of gaze dwells)
are associated with detection accuracy. During image interpretation,
the reader's eye movements are tracked unobtrusively with a video came
ra mounted below the monitor displaying the images. The eye movement i
nformation is used to identify regions of prolonged dwell, which are a
ssociated with false-positive detection of pulmonary nodules. Based on
the locations of the dwell regions, a small, circular region of inter
est is created within the image. Real-time digital processing can then
be performed within this region of interest. Such processing can be p
erformed as the reader is looking at the image or after the image has
been interpreted. Readers' eye movements can be used to direct localiz
ed image enhancement and analysis during interpretation of digital che
st radiographs.