SYNTHESIS OF 5H-THIAZOLO[3,2-A]PYRIMIDINE DERIVATIVES FROM 6-METHYL-2-THIOURACIL AND 1-ACYL-2-BROMOACETYLENES - X-RAY STRUCTURAL STUDY OF BENZOYL-7-METHYL-5H-THIAZOLO[3,2-A]PYRIMIDIN-5-ONE

Authors
ELOKHINA VN NAKHMANOVICH AS STEPANOVA ZV LOPYREV VA BANNIKOVA OB STRUCHKOV YT SHISHKIN OV
Citation
Vn. Elokhina et al., SYNTHESIS OF 5H-THIAZOLO[3,2-A]PYRIMIDINE DERIVATIVES FROM 6-METHYL-2-THIOURACIL AND 1-ACYL-2-BROMOACETYLENES - X-RAY STRUCTURAL STUDY OF BENZOYL-7-METHYL-5H-THIAZOLO[3,2-A]PYRIMIDIN-5-ONE, Russian chemical bulletin, 45(9), 1996, pp. 2189-2191
Citations number
7
Categorie Soggetti
Chemistry
Journal title
Russian chemical bulletin → ACNP
ISSN journal
10665285
Volume
45
Issue
9
Year of publication
1996
Pages
2189 - 2191
Database
ISI
SICI code
1066-5285(1996)45:9<2189:SO5DF6>2.0.ZU;2-R
Abstract
3-Acyl-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-ones were synthesized by the reaction of 1-acyl-2-bromoacetylenes with 6-methyl-2-thiouracil, carried out with heating in DMF, dioxane, or acetonitrile in the prese nce of triethylamine. The structure of benzoyl-7-methyl-5H-thiazolo[3, 2-a]pyrimidin-5-one was established by X-ray structural analysis.