EFFECT OF SUCRALFATE ON HEALING OF SUBCLINICAL GASTRIC-ULCERS IN FOALS

Citation
At. Borne et Cg. Macallister, EFFECT OF SUCRALFATE ON HEALING OF SUBCLINICAL GASTRIC-ULCERS IN FOALS, Journal of the American Veterinary Medical Association, 202(9), 1993, pp. 1465-1468
Citations number
45
Categorie Soggetti
Veterinary Sciences
ISSN journal
00031488
Volume
202
Issue
9
Year of publication
1993
Pages
1465 - 1468
Database
ISI
SICI code
0003-1488(1993)202:9<1465:EOSOHO>2.0.ZU;2-U
Abstract
The effect of sucralfate on healing of subclinical gastric ulcers and gastric inflammation was investigated in twelve 6- to 7-month-old foal s. Foals with endoscopically evident gastric lesions on day 0 were ass igned to 1 of 2 groups, on the basis of mucosal inflammation and numbe r and severity of ulcers, to create groups of foals with approximately equal severity of lesions. None of these foals had clinical signs of gastroduodenal ulcer disease. Groups were assigned to receive sucralfa te (22.0 mg/kg of body weight) or corn syrup for 14 days, PO, every 8 hours. On day 15, gastroscopic examinations revealed that sucralfate d id not promote greater healing than did the corn syrup.